Publications

Kumatani, A.; Sato, Y.; Takahashi, Y.; Ida, H.; Shiku, H.; Matsue, T.; Komaba, S., Local electrochemical signatures and SEI formation pathways in silicon-graphite composite negative electrodes. Chemical Engineering Journal 2026, 180693.

Honda, K.; Hirata, K.; Amano, F.; Fukuma, T.; Takahashi, Y., Facet-Dependent Photoelectrochemical Oxidation on Particle-Based BiVO4 Photoanode Investigated by Scanning Electrochemical Cell Microscopy. ACS Energy Letters 2026, 11 (6), 4698-4704.

Kembishi, H.; Saijo, N.; Endo, K.; Hisatomi, T.; Takahashi, Y.; Hirata, K.; Nishiyama, H.; Domen, K.; Onishi, H., High-speed analysis of oxygen evolution kinetics using microamperometry: application to a SrTiO3 photocatalyst sheet. Journal of Catalysis 2026, 116957.

Kumatani, A.; Tachizaki, E.; Ishige, R.; Ida, H.; Takahashi, Y.; Shiraki, S.; Shiku, H., Raman-integrated scanning electrochemical cell microscopy for operando localized spectroelectrochemistry. Applied Physics Letters 2026, 128 (16).

Sugiyama, K.; Sato, F.; Kunitastu, Y.; Honda, K.; Hirabayashi, Y.; Takahashi, Y.; Sato, K., Facile and Rapid Fabrication of a Glutamate Sensor via Electropolymerization of o-Aminophenol. Electrochemical Science Advances 2026, 6 (2), e70022 .

Kofuji, S.; Sumita, K.; Ikeda, Y.; Takahashi, Y.; Tabata, S.; Ito, D.; Hirota, Y.; Sasaki, M.; Kanoh, H.; Nakatsu, F.; Takeuchi, K.; Senda, T.; Davis, M. I.; Shen, M.; Wakimoto, H.; Hirayama, A.; Soga, T.; Simeonov, A.; Sasaki, A. T., Polypharmacologic phosphoinositide modulation by FTY720 triggers endomembrane trafficking collapse and metabolic starvation in cancer cells. Biochemical and Biophysical Research Communications 2026, 153671.

Cheng, X.; Nishimura, T.; Yamase, R.; Nishikawa, H.; Mandal, S.; Das, S.; Ueno, M.; Arakawa, H.; Rahman, S.; Hasegawa, H.; Ogoshi, T.; Takahashi, Y.; Korchev, Y.; Hirao, A.; Zhang, Y.; Maeda, K., Functionalized Pillar[6]arene Nanomembrane Probe for Ultrasensitive Sensing of Clinically Valuable 1-Methylnicotinamide in Mouse Urine. Nano Letters 2026, 26 (3), 944-952.

Suzuki, H.; Hirata, K.; Takahashi, Y.; Fujii, S.; Misawa, M.; Tokunaga, T.; Nakaya, I.; Senda, Y.; Hayashi, Y.; Takahashi, Y., Dendritic WS2 Nanoribbon Networks Grown in Interfacial Confinement Space: Edge-Rich Architectures for Enhanced Hydrogen Evolution. Small Structures 2026, 7 (1), e202500542 .

Tachizaki, E.; Sato, A.; Ida, H.; Takahashi, Y.; Shiku, H.; Kumatani, A., Electrochemical pipette-based analysis on anisotropy in rutile TiO2 for photoelectrochemical hydrogen revolution. Journal of Vacuum Science & Technology B 2025, 43 (5), 1.

Sakakibara, R.; Hirata, K.; Takahashi, Y.; Norimatsu, W.; Miyata, Y., Improved strain engineering of monolayer transition metal dichalcogenides via van der Waals epitaxy on graphene/SiC (0001). Nano Letters 2025, 25 (34), 12851–12858.

Ida, H.; Yoshida, T.; Kumatani, A.; Hanayama, R.; Takahashi, Y., Direct Extraction and Evaluation of Intraluminal Vesicles Inside a Single Cell. Nano Lett 2025, 25 (11), 4322-4329.

Minegishi, T.; Hasebe, H.; Aoyama, T.; Naruse, K.; Takahashi, Y.; Inagaki, N., Mechanical signaling through membrane tension induces somal translocation during neuronal migration. Embo J 2025, 44 (3), 767-780.

Usuda, J.; Yagyu, K.; Tanaka, H.; Hori, M.; Ishikawa, K.; Takahashi, Y., Nanoscale visualization of the anti-tumor effect of a plasma-activated Ringer's lactate solution. Faraday Discuss 2025, 257 (0), 212-223.

Ma, Z.; Solis-Fernandez, P.; Hirata, K.; Lin, Y. C.; Shinokita, K.; Maruyama, M.; Honda, K.; Kato, T.; Uchida, A.; Ogura, H.; Otsuka, T.; Hara, M.; Matsuda, K.; Suenaga, K.; Okada, S.; Kato, T.; Takahashi, Y.; Ago, H., Lattice-guided growth of dense arrays of aligned transition metal dichalcogenide nanoribbons with high catalytic reactivity. Sci Adv 2025, 11 (2), eadr8046.

Nakanishi, Y.; Kanda, N.; Aizaki, M.; Hirata, K.; Takahashi, Y.; Endo, T.; Lin, Y. C.; Senga, R.; Suenaga, K.; Aoyagi, S.; Maruyama, M.; Gao, Y. L.; Okada, S.; Miyata, Y.; Liu, Z., Superatomic Layer of Cubic Mo S Clusters Connected by Cl Cross-Linking. Adv Mater 2024, 36 (39).

Vaneev, A. N.; Gorelkin, P. V.; Akasov, R. A.; Timoshenko, R. V.; Lopatukhina, E. V.; Garanina, A. S.; Abakumova, T. O.; Aleksandrin, V. V.; Salikhov, S. V.; Edwards, C. R. W.; Takahashi, Y.; Klyachko, N. L.; Korchev, Y. E.; Erofeev, A. S., oxygen electrochemical nanosensor for bioanalysis. J Electroanal Chem 2024, 975.

Pirabul, K.; Pan, Z. Z.; Kanamaru, K.; Horiguchi, Y.; Takahashi, Y.; Kumatani, A.; Nishihara, H., Probing non-Faradaic process during elastic deformation in a single sphere of extremely soft mesoporous carbon. Carbon 2024, 228.

Kumatani, A.; Ogawa, H.; Endo, T.; Lustikova, J.; Ida, H.; Takahashi, Y.; Miyata, Y.; Ikuhara, Y.; Shiku, H.; Wakayama, Y., Emergence of electrochemical catalytic activity via an electrochemical-probe on defective transition metal dichalcogenide nanosheets. APL Energy 2024, 2 (1).

Kaneda, M.; Zhang, W.; Liu, Z.; Gao, Y.; Maruyama, M.; Nakanishi, Y.; Nakajo, H.; Aoki, S.; Honda, K.; Ogawa, T.; Hashimoto, K.; Endo, T.; Aso, K.; Chen, T.; Oshima, Y.; Yamada-Takamura, Y.; Takahashi, Y.; Okada, S.; Kato, T.; Miyata, Y., Nanoscrolls of Janus Monolayer Transition Metal Dichalcogenides. Acs Nano 2024, 18 (4), 2772-2781.

Timoshenko, R. V.; Gorelkin, P. V.; Vaneev, A. N.; Krasnovskaya, O. O.; Akasov, R. A.; Garanina, A. S.; Khochenkov, D. A.; Iakimova, T. M.; Klyachko, N. L.; Abakumova, T. O.; Shashkovskaya, V. S.; Chaprov, K. D.; Makarov, A. A.; Mitkevich, V. A.; Takahashi, Y.; Edwards, C. R. W.; Korchev, Y. E.; Erofeev, A. S., Electrochemical Nanopipette Sensor for In Vitro/In Vivo Detection of Cu2+ Ions. Analytical Chemistry 2024, 96 (1), 127-136.

Kumatani, A.; Miura, C.; Ida, H.; Takahashi, Y.; Ikuhara, Y.; Shiku, H.; Matsue, T.; Okada, T., Comprehensive electrochemical imaging analyses of redox activities correlated to multilayer graphene and graphite structures. Electrochim Acta 2024, 499.

Takahashi, Y.; Sasaki, Y.; Yoshida, T.; Honda, K.; Zhou, Y.; Miyamoto, T.; Motoo, T.; Higashi, H.; Shevchuk, A.; Korchev, Y.; Ida, H.; Hanayama, R.; Fukuma, T., Nanopipette Fabrication Guidelines for SICM Nanoscale Imaging. Analytical Chemistry 2023, 95 (34), 12664-12672.

Sugiyama, K.; Sato, F.; Komatsu, S.; Kamijo, T.; Yoshida, K.; Kawabe, Y.; Nishikawa, H.; Fujimura, T.; Takahashi, Y.; Sato, K., Highly sensitive glucose electrochemical sensor using sugar-lectin interactions. Electrochemical Science Advances 2023, n/a (n/a), e2300015.

Sato, F.; Nakano, H.; Kamijo, T.; Watanabe, K.; Fujimura, T.; Takahashi, Y.; Sato, K., Vancomycin sensing using a phenylboronic acid-modified nanopore pipette. Electroanal 2023, 35 (11), e202300173.

Kumatani, A.; Ogawa, H.; Endo, T.; Kobayashi, Y.; Lustikova, J.; Ida, H.; Takahashi, Y.; Matsue, T.; Miyata, Y.; Shiku, H., Electrochemical imaging correlated to hydrogen evolution reaction on transition metal dichalcogenide, WS2. J Vac Sci Technol B 2023, 41 (5).

Kobayashi, Y.; Yokota, Y.; Takahashi, Y.; Takeya, J.; Kim, Y., Electrodeposited Gold Probe for Electrochemical Scanning Tunneling Microscopy. J Phys Chem C 2023, 127 (28), 13929-13935.

Kawabe, Y.; Ito, Y.; Hori, Y.; Kukunuri, S.; Shiokawa, F.; Nishiuchi, T.; Jeong, S.; Katagiri, K.; Xi, Z. Y.; Li, Z. K.; Shigeta, Y.; Takahashi, Y., 1T/1H-SnS2 Sheets for Electrochemical CO2 Reduction to Formate. Acs Nano 2023, 17 (12), 11318-11326.

Takahashi, Y.; Takamatsu, D.; Korchev, Y.; Fukuma, T., Correlative Analysis of Ion-Concentration Profile and Surface Nanoscale Topography Changes Using Operando Scanning Ion Conductance Microscopy. Jacs Au2023, 3 (4), 1089-1099.

Nozawa, K.; Zhang, X.; Nakamura, T.; Nashimoto, Y.; Takahashi, Y.; Ino, K.; Shiku, H., Topographical evaluation of human mesenchymal stem cells during osteogenic differentiation using scanning ion conductance microscopy. Electrochim. Acta 2023, 449, 142192.

Ida, H.; Taira, N.; Azuma, K.; Kumatani, A.; Akishiba, M.; Futaki, S.; Takahashi, Y.; Shiku, H., Surface morphology live-cell imaging reveals how macropinocytosis inhibitors affect membrane dynamics. Electrochim. Acta 2023, 441, 141783.

Hirai, K.; Ishikawa, H.; Takahashi, Y.; Hutchison, J. A.; Uji-i, H., Autotuning of Vibrational Strong Coupling for Site-Selective Reactions. Chemistry – A European Journal 2022, 28 (47), e202201260.

Hirose, H.; Maekawa, M.; Ida, H.; Kuriyama, M.; Takahashi, Y.; Futaki, S., A noncanonical endocytic pathway is involved in the internalization of 3 um polystyrene beads into HeLa cells. Biomater Sci-Uk 2022.

Vaneev, A. N.; Gorelkin, P. V.; Krasnovskaya, O. O.; Akasov, R. A.; Spector, D. V.; Lopatukhina, E. V.; Timoshenko, R. V.; Garanina, A. S.; Zhang, Y.; Salikhov, S. V.; Edwards, C. R. W.; Klyachko, N. L.; Takahashi, Y.; Majouga, A. G.; Korchev, Y. E.; Erofeev, A. S., In Vitro/In Vivo Electrochemical Detection of Pt(II) Species. Anal Chem2022, 94 (12), 4901-4905.

Makarova, M. V.; Amano, F.; Nomura, S.; Tateishi, C.; Fukuma, T.; Takahashi, Y.; Korchev, Y. E., Direct Electrochemical Visualization of the Orthogonal Charge Separation in Anatase Nanotube Photoanodes for Water Splitting. Acs Catal2022, 12 (2), 1201-1208.

Yamamoto, T.; Ando, T.; Kawabe, Y.; Fukuma, T.; Enomoto, H.; Nishijima, Y.; Matsui, Y.; Kanamura, K.; Takahashi, Y., Characterization of the Depth of Discharge-Dependent Charge Transfer Resistance of a Single LiFePO4 Particle. Analytical Chemistry2021, 93 (43), 14448-14453.

Kosaka, T.; Ando, T.; Hisatomi, T.; Nishiyama, H.; Zhou, Y.; Domen, K.; Takahashi, Y.; Onishi, H., Microelectrode-Based Transient Amperometry of O2 Adsorption and Desorption on a SrTiO3 Photocatalyst Excited under Water. Physical Chemistry Chemical Physics 2021, 23, 19386–19393.

Nashimoto, Y.; Abe, M.; Fujii, R.; Taira, N.; Ida, H.; Takahashi, Y.; Ino, K.; Ramon-Azcon, J.; Shiku, H., Topography and Permeability Analyses of Vasculature-on-a-Chip Using Scanning Probe Microscopies. Adv Healthc Mater 2021, e2101186.

Kanno, Y.; Zhou, Y. S.; Fukuma, T.; Takahashi, Y., Alkaline Phosphatase-based Electrochemical Analysis for Point-of-care Testing. Electroanal2021.

Kawabe, Y.; Miyakoshi, Y.; Tang, R.; Fukuma, T.; Nishihara, H.; Takahashi, Y., Nanoscale characterization of the site-specific degradation of electric double-layer capacitor using scanning electrochemical cell microscopy. Electrochemical Science Advances 2021, n/a (n/a), e2100053.

Ida, H.; Takahashi, Y.; Kumatani, A.; Shiku, H.; Murayama, T.; Hirose, H.; Futaki, S.; Matsue, T., Nanoscale Visualization of Morphological Alteration of Live-Cell Membranes by the Interaction with Oligoarginine Cell-Penetrating Peptides. Anal Chem 2021, 93 (13), 5383-5393.

Sato, K.; Sato, F.; Kumano, M.; Kamijo, T.; Sato, T.; Zhou, Y. S.; Korchev, Y.; Fukuma, T.; Fujimura, T.; Takahashi, Y., Electrochemical Quantitative Evaluation of the Surface Charge of a Poly(1-vinylimidazole) Multilayer Film and Application to Nanopore pH Sensor. Electroanal2021, 33 (6), 1633-1638.

Zhou, Y.; Takahashi, Y.; Fukuma, T.; Matsue, T., Scanning electrochemical microscopy for biosurface imaging. Current Opinion in Electrochemistry2021, 100739.

Ando, T.; Asai, K.; Macpherson, J.; Einaga, Y.; Fukuma, T.; Takahashi, Y., Nanoscale Reactivity Mapping of a Single-Crystal Boron-Doped Diamond Particle. Analytical Chemistry 2021, 93 (14), 5831-5838.

Ida, H.; Takahashi, Y.; Kumatani, A.; Shiku, H.; Murayama, T.; Hirose, H.; Futaki, S.; Matsue, T., Nanoscale Visualization of Morphological Alteration of Live-Cell Membranes by the Interaction with Oligoarginine Cell-Penetrating Peptides. Analytical Chemistry 2021, 93 (13), 5383-5393.

Taira, N.; Nashimoto, Y.; Ino, K.; Ida, H.; Imaizumi, T.; Kumatani, A.; Takahashi, Y.; Shiku, H., Micropipet-Based Navigation in a Microvascular Model for Imaging Endothelial Cell Topography Using Scanning Ion Conductance Microscopy. Analytical Chemistry 2021, 93 (11), 4902-4908.

Tsujiguchi, T.; Kawabe, Y.; Jeong, S.; Ohto, T.; Kukunuri, S.; Kuramochi, H.; Takahashi, Y.; Nishiuchi, T.; Masuda, H.; Wakisaka, M.; Hu, K.; Elumalai, G.; Fujita, J.-i.; Ito, Y., Acceleration of Electrochemical CO2 Reduction to Formate at the Sn/Reduced Graphene Oxide Interface. Acs Catal 2021, 11 (6), 3310-3318.

Kolmogorov, V. S.; Erofeev, A. S.; Woodcock, E.; Efremov, Y. M.; Iakovlev, A. P.; Savin, N. A.; Alova, A. V.; Lavrushkina, S. V.; Kireev, I. I.; Prelovskaya, A. O.; Sviderskaya, E. V.; Scaini, D.; Klyachko, N. L.; Timashev, P. S.; Takahashi, Y.; Salikhov, S. V.; Parkhomenko, Y. N.; Majouga, A. G.; Edwards, C. R. W.; Novak, P.; Korchev, Y. E.; Gorelkin, P. V., Mapping mechanical properties of living cells at nanoscale using intrinsic nanopipette–sample force interactions. Nanoscale 2021, 13 (13), 6558-6568.

Kosaka, T.; Teduka, Y.; Ogura,T.; Zhou,Y.; Hisatomi, T.; Nishiyama, H.; Domen, K.;Takahashi, Y.; Onishi, H., Transient Kinetics of O2 Evolution in Photocatalytic Water-Splitting Reaction. ACS Catalysis, 2020, 10 (22), 13159-13164.

Takahashi, Y.; Yamashita, T.; Takamatsu, D.; Kumatani, A.; Fukuma, T., Nanoscale kinetic imaging of lithium ion secondary battery materials using scanning electrochemical cell microscopy. Chem Commun 2020, 56 (65), 9324-9327.

Vaneev, A. N.; Gorelkin, P. V.; Garanina, A. S.; Lopatukhina, H. V.; Vodopyanov, S. S.; Alova, A. V.; Ryabaya, O. O.; Akasov, R. A.; Zhang, Y.; Novak, P.; Salikhov, S. V.; Abakumov, M. A.; Takahashi, Y.; Edwards, C. R. W.; Klyachko, N. L.; Majouga, A. G.; Korchev, Y. E.; Erofeev, A. S., In Vitro and In Vivo Electrochemical Measurement of Reactive Oxygen Species After Treatment with Anticancer Drugs. Anal Chem 2020, 92 (12), 8010-8014.

Yasuda, S.; Tamura, K.; Terasawa, T.; Yano, M.; Nakajima, H.; Morimoto, T.; Okazaki, T.; Agari, R.; Takahashi, Y.; Kato, M.; Yagi, I.; Asaoka, H., Confinement of Hydrogen Molecules at Graphene-Metal Interface by Electrochemical Hydrogen Evolution Reaction. J Phys Chem C2020, 124 (9), 5300-5307.

Takahashi, Y.; Zhou, Y.; Miyamoto, T.; Higashi, H.; Nakamichi, N.; Takeda, Y.; Kato, Y.; Korchev, Y.; Fukuma, T., High-Speed SICM for the Visualization of Nanoscale Dynamic Structural Changes in Hippocampal Neurons. Anal Chem2020, 92 (2), 2159-2167.

Zhang, Y.; Takahashi, Y.; Hong, S. P.; Liu, F.; Bednarska, J.; Goff, P. S.; Novak, P.; Shevchuk, A.; Gopal, S.; Barozzi, I.; Magnani, L.; Sakai, H.; Suguru, Y.; Fujii, T.; Erofeev, A.; Gorelkin, P.; Majouga, A.; Weiss, D. J.; Edwards, C.; Ivanov, A. P.; Klenerman, D.; Sviderskaya, E. V.; Edel, J. B.; Korchev, Y., High-resolution label-free 3D mapping of extracellular pH of single living cells. Nat Commun2019, 10 (1), 5610.

Kumatani, A.; Miura, C.; Kuramochi, H.; Ohto, T.; Wakisaka, M.; Nagata, Y.; Ida, H.; Takahashi, Y.; Hu, K.; Jeong, S.; Fujita, J.-i.; Matsue, T.; Ito, Y., Chemical Dopants on Edge of Holey Graphene Accelerate Electrochemical Hydrogen Evolution Reaction. Advanced Science2019, 6 (10), 1900119.

Kumatani, A.; Takahashi, Y.; Miura, C.; Ida, H.; Inomata, H.; Shiku, H.; Munakata, H.; Kanamura, K.; Matsue, T., Scanning Electrochemical Cell Microscopy for Visualization and Local Electrochemical Activities of Lithium-Ion (De)intercalation Process in Lithium-Ion Batteries Electrodes, Surface and Interface Analysis 2019, 51, 27-30.

Inomata, H.; Takahashi, Y.; Takamatsu, D.; Kumatani, A.; Ida, H.; Shiku, H.; Matsue, T., Visualization of inhomogeneous current distribution on ZrO2-coated LiCoO2 thin-film electrodes using scanning electrochemical cell microscopy. Chem Commun 2019, 55 (4), 545-548.

Zhou, Y.; Saito, M.; Miyamoto, T.; Novak, P.; Shevchuk, A. I.; Korchev, Y. E.; Fukuma, T.; Takahashi, Y., Anal. Chem. 2018, 90, 2891–2895.

Takahashi, Y.; Zhou, Y.; Fukuma, T., Development of carbon-based nanoelectrodes for biosensing and electrochemical imaging, Current Opinion in Electrochemistry 2017, 5, 121-125.

Takahashi, Y.; Ida, H.; Matsumae, Y.; Komaki, H.; Zhou, Y.; Kumatani, A.; Kanzaki, M.; Shiku, H.; Matsue, T., 3D electrochemical and ion current imaging using scanning electrochemical-scanning ion conductance microscopy. PCCP 2017, 19 (39), 26728-26733.

Murayama, T.; Masuda, T,; Afonin, S.; Kawano, K.; Takatani- Nakase, T.; Ida, H.; Takahashi, Y.; Fukuma, T.; Ulrich, S.; Futaki, S., Loosening of Lipid Packing Promotes Oligoarginine Entry into Cells, Angew. Chem. Int. Ed. 2017, 56, 1 – 7.

Ida, H.; Takahashi, Y.; Kumatani, A.; Shiku, H.; Matsue, T., High Speed Scanning Ion Conductance Microscopy for Quantitative Analysis of Nanoscale Dynamics of Microvilli. Anal. Chem. 2017, 89 (11), 6015-6020.

Takahashi, Y.; Kumatani, A.; Shiku, H.; Matsue, T., Scanning Probe Microscopy for Nanoscale Electrochemical Imaging. Anal. Chem. 2017,　89, 342–357.

Hibino, H.; Takai, M.; Noguchi, H.; Sawamura, S.; Takahashi, Y., Sakai, H.; Shiku, H., An approach to the research on ion and water properties in the interphase between the plasma membrane and bulk extracellular solution, The Journal of Physiological Sciences 2017, 1-7 .

Matsuoka, R.; Aoyagi, S.; Matsumoto, N.; Matsudaira, M.; Takahashi, Y.; Kumatani, A.; Ida, H.; Munakata, H.; Iida, K.; Shiku, H.; Kanamura, K.; Matsue, T., Advanced Scanning Electrochemical Microscope System for High-Resolution imaging and Electrochemical Applications. Electrochemistry 2017, 85 (6), 319-326.

Ito, H.; Tanaka, M.; Zhou, Y.; Nashimoto, Y.; Takahashi, Y.; Ino, K.; Matsue, T.; Shiku, H., Anal. Bioanal. Chem. 2017, 409, 961-969.

Takahashi, Y.; Development of high-resolution scanning electrochemical microscopy for nanoscale topography and electrochemical simultaneous imaging, Electrochemistry 2016, 84 662-666.

Zhang, Y.; Clausmeyer, J.; Babakinejad, B.; Lopez Cordoba, A.; Ali, T.; Shevchuk, A.; Takahashi, Y.; Novak, P.; Edwards, C.; Lab, M.; Gopal, S.; Chiappini, C.; Anand, U.; Magnani, L.; Coombes, R. C.; Gorelik, J.; Matsue, T.; Schuhmann, W.; Klenerman, D.; Sviderskaya, E. V.; Korchev, Y., Spearhead Nanometric Field-Effect Transistor Sensors for Single-Cell Analysis. Acs Nano 2016, 10 (3), 3214-21.

Nashimoto, Y.; Takahashi, Y.; Zhou, Y.; Ito, H.; Ida, H.; Ino, K.; Matsue, T.; Shiku, H., Evaluation of mRNA Localization Using Double Barrel Scanning Ion Conductance Microscopy. Acs Nano 2016, 10 (7), 6915-22.

Ito, H.; Nashimoto, Y.; Zhou, Y.; Takahashi, Y.; Ino, K.; Shiku, H.; Matsue, T., Localized Gene Expression Analysis during Sprouting Angiogenesis in Mouse Embryoid Bodies Using a Double Barrel Carbon Probe. Anal. Chem. 2016, 88 (1), 610-3.

Takano, S.; Inoue, K. Y.; Ikegawa, M.; Takahashi, Y.; Ino, K.; Shiku, H.; Matsue, T., Liquid-junction-free system for substitutional stripping voltammetry using a closed bipolar electrode system. Electrochem. Commun. 2016, 66, 34-37.

Ida, H.; Ino, K.; Suzuki, J.; Takahashi, Y.; Shiku, H.; Matsue, T., Redox Cycling-based Electrochemical Reporter Gene Assay for Single Cells Using a Scanning Electrochemical Microscope-microwell System. Electrochemistry 2016, 84 (5), 308-311.

Abe, H.; Ino, K.; Li, Chen.; Kanno, Y.; Inoue, K.; Suda, A.; Kunikata, Ｒ.; Matsudaira, Ｍ.; Takahashi, Ｙ.; Shiku, H.; Matsue, T., Electrochemical imaging of dopamine release from three-dimensional-cultured PC12 cells using LSI-based amperometric sensors. Anal. Chem., 2015, 87, 6364-6370.

Şen, M.; Takahashi, Y.; Matsumae, Y.; Horiguchi, Y.; Kumatani, A.; Ino, K.; Shiku, H.; Matsue, T., Improving the electrochemical imaging sensitivity of scanning electrochemical microscopy-scanning ion conductance microscopy by using electrochemical Pt deposition. Anal. Chem., 2015, 87, 3484–3489.

Nashimoto, Y.; Takahashi, Y.; Ida, H.; Matsumae, Y.; Ino, K.; Shiku, H.; Matsue, T., Nanoscale imaging of an unlabeled secretory protein in living cells using scanning ion conductance microscopy. Anal. Chem., 2015, 87, 2542–2545.

Takahashi, Y.; Kumatani, A.; Munakata, H.; Inomata, H.; Ito, K.; Ino, K.; Shiku, H.; Unwin, PR.; Korchev, YE.; Kanamura, K.; Matsue, T., Nanoscale visualisation of redox activity and Li+ (de)intercalation dynamics at LiFePO4 battery cathodes. Nature Commun., 2014, 5.

Matsumae, Y.; Takahashi, Y.; Ino, K.; Shiku, H.; Matsue, T., Electrochemical Monitoring of Intracellular Enzyme Activity of Single Living Mammalian Cells by Using a Double-Mediator System. Anal. Chim. Acta, 2014, 842, 20-26.

Takahashi, Y. ; Ito, K.; Xiongwe, W.; Matsumae, Y.; Komaki, H.; Kumatani, A.; Ino, K.; Shiku, H.; Matsue, T., Nanoscale Cell Surface Topography Imaging using Scanning Ion Conductance Microscopy. Electrochemistry, 2014, 82, 331-334.

Nashimoto, Y.; Takahashi, Y.; Takano, R.; Miyashita, K.; Yamada, S.; Ino, K.; Shiku, H.; Matsue, T., Isolation and quantification of messenger RNA from tissue models by using a double-barrel carbon probe. Anal. Bioanal. Chem. 2014, 406 (1), 275-282.

Kanno, Y.; Goto, T.; Ino, K.; Inoue, K. Y.; Takahashi, Y.; Shiku, H.; Matsue, T., SU-8-based Flexible Amperometric Device with IDA Electrodes to Regenerate Redox Species in Small Spaces. Anal. Sci. 2014, 30 (2), 305-309.

Ino, K.; Kanno, Y.; Nishijo, T.; Komaki, H.; Yamada, Y.; Yoshida, S.; Takahashi, Y.; Shiku, H.; Matsue, T., Densified Electrochemical Sensors Based on Local Redox Cycling between Vertically Separated Electrodes in Substrate Generation/Chip Collection and Extended Feedback Modes. Anal. Chem. 2014, 86 (8), 4016-23.

Ino, K.; Goto, T.; Kanno, Y.; Inoue, K. Y.; Takahashi, Y.; Shiku, H.; Matsue, T., Droplet array on local redox cycling-based electrochemical (LRC-EC) chip device. Lab Chip 2014, 14 (4), 787-794.

Actis, P.; Tokar, S.; Clausmeyer, J.; Babakinejad, B.; Mikhaleva, S.; Cornut, R.; Takahashi, Y.; Cordoba, A. L.; Novak, P.; Shevchuck, A. I.; Dougan, J. A.; Kazarian, S. G.; Gorelkin, P. V.; Erofeev, A. S.; Yaminsky, I. V.; Unwin, P. R.; Schuhmann, W.; Klenerman, D.; Rusakov, D. A.; Sviderskaya, E. V.; Korchev, Y. E., Electrochemical Nanoprobes for Single-Cell Analysis. Acs Nano 2014, 8 (1), 875-884.

Ozawa, F.; Ino, K.; Takahashi, Y.; Shiku, H.; Matsue, T., Electrodeposition of alginate gels for construction of vascular-like structures. J. Biosci. Bioeng. 2013, 115 (4), 459-461.

Ozawa, F.; Ino, K.; Arai, T.; Ramon-Azcon, J.; Takahashi, Y.; Shiku, H.; Matsue, T., Alginate gel microwell arrays using electrodeposition for three-dimensional cell culture. Lab Chip 2013, 13 (15), 3128-3135.

McKelvey, K.; Nadappuram, B. P.; Actis, P.; Takahashi, Y.; Korchev, Y. E.; Matsue, T.; Robinson, C.; Unwin, P. R., Fabrication, Characterization, and Functionalization of Dual Carbon Electrodes as Probes for Scanning Electrochemical Microscopy (SECM). Anal. Chem. 2013, 85 (15), 7519-7526.

Matsumae, Y.; Arai, T.; Takahashi, Y.; Ino, K.; Shiku, H.; Matsue, T., Evaluation of the differentiation status of single embryonic stem cells using scanning electrochemical microscopy. Chem. Commun. 2013, 49 (58), 6498-6500.
Ino, K.; Ono, K.; Arai, T.; Takahashi, Y.; Shiku, H.; Matsue, T., Carbon-Ag/AgCl Probes for Detection of Cell Activity in Droplets. Anal. Chem. 2013, 85 (8), 3832-3835.

Ino, K.; Nishijo, T.; Kanno, Y.; Ozawa, F.; Arai, T.; Takahashi, Y.; Shiku, H.; Matsue, T., Electrochemical Device with Interdigitated Ring Array Electrodes for Investigating the Relationship between Cardiomyocyte Differentiation from Embryonic Stem Cells and Alkaline Phosphatase Activity. Electrochemistry 2013, 81 (9), 682-687.

Babakinejad, B.; Jonsson, P.; Cordoba, A. L.; Actis, P.; Novak, P.; Takahashi, Y.; Shevchuk, A.; Anand, U.; Anand, P.; Drews, A.; Ferrer-Montiel, A.; Klenerman, D.; Korchev, Y. E., Local Delivery of Molecules from a Nanopipette for Quantitative Receptor Mapping on Live Cells. Anal. Chem. 2013, 85 (19), 9333-9342.

Ino, K.; Nishijo, T.; Arai, T.; Kanno, Y.; Takahashi, Y.; Shiku, H.; Matsue, T., Local Redox-Cycling-Based Electrochemical Chip Device with Deep Microwells for Evaluation of Embryoid Bodies. Angew. Chem. Int. Ed. 2012, 51 (27), 6648-6652.

Takahashi, Y.; Shevchuk, A. I.; Novak, P.; Babakinejad, B.; Macpherson, J.; Unwin, P. R.; Shiku, H.; Gorelik, J.; Klenerman, D.; Korchev, Y. E.; Matsue, T., Topographical and electrochemical nanoscale imaging of living cells using voltage-switching mode scanning electrochemical microscopy. Proc. Natl. Acad. Sci. U. S. A. 2012, 109 (29), 11540-11545 7593-7598.

Ino, K.; Kanno, Y.; Nishijo, T.; Goto, T.; Arai, T.; Takahashi, Y.; Shiku, H.; Matsue, T., Electrochemical detection for dynamic analyses of a redox component in droplets using a local redox cycling-based electrochemical (LRC-EC) chip device. Chem. Commun. 2012, 48 (68), 8505-8507.

Ino, K.; Kanno, Y.; Arai, T.; Inoue, K. Y.; Takahashi, Y.; Shiku, H.; Matsue, T., Novel Electrochemical Methodology for Activity Estimation of Alkaline Phosphatase Based on Solubility Difference. Anal. Chem. 2012, 84 (18), 7593-7598.

Takahashi, Y.; Shevchuk, A. I.; Novak, P.; Zhang, Y. J.; Ebejer, N.; Macpherson, J. V.; Unwin, P. R.; Pollard, A. J.; Roy, D.; Clifford, C. A.; Shiku, H.; Matsue, T.; Klenerman, D.; Korchev, Y. E., Multifunctional Nanoprobes for Nanoscale Chemical Imaging and Localized Chemical Delivery at Surfaces and Interfaces. Angew. Chem. Int. Ed. 2011, 50 (41), 9638-9642.

Takahashi, Y.; Miyamoto, T.; Shiku, H.; Ino, K.; Yasukawa, T.; Asano, R.; Kumagai, I.; Matsue, T., Electrochemical detection of receptor-mediated endocytosis by scanning electrochemical microscopy. PCCP 2011, 13 (37), 16569-16573.

Shevchuk, A. I.; Novak, P.; Takahashi, Y.; Clarke, R.; Miragoli, M.; Babakinejad, B.; Gorelik, J.; Korchev, Y. E.; Klenerman, D., Realizing the biological and biomedical potential of nanoscale imaging using a pipette probe. Nanomedicine 2011, 6 (3), 565-575.

Nagamine, K.; Takahashi, Y.; Ino, K.; Shiku, H.; Matsue, T., Influence of Tip Size on Single Yeast Cell Imaging Using Scanning Electrochemical Microscopy. Electroanal 2011, 23 (5), 1168-1174.

Takahashi, Y.; Shevchuk, A. I.; Novak, P.; Murakami, Y.; Shiku, H.; Korchev, Y. E.; Matsue, T., Simultaneous Noncontact Topography and Electrochemical Imaging by SECM/SICM Featuring Ion Current Feedback Regulation. J. Am. Chem. Soc. 2010, 132 (29), 10118-10126.

Takahashi, Y.; Murakami, Y.; Nagamine, K.; Shiku, H.; Aoyagi, S.; Yasukawa, T.; Kanzaki, M.; Matsue, T., Topographic imaging of convoluted surface of live cells by scanning ion conductance microscopy in a standing approach mode. PCCP 2010, 12 (34), 10012-10017.

Shiku, H.; Okazaki, D.; Suzuki, J.; Takahashi, Y.; Murata, T.; Akita, H.; Harashima, H.; Ino, K.; Matsue, T., Reporter gene expression at single-cell level characterized with real-time RT-PCR, chemiluminescence, fluorescence, and electrochemical imaging. FEBS Lett. 2010, 584 (18), 4000-4008.

Shiku, H.; Kumagai, A.; Luo, H. Q.; Takahashi, Y.; Yasukawa, T.; Yamada, H.; Matsue, T., Electrochemical Characterization of Enzyme and Immunoglobulin G Patterned Using Microcontact Printing. Electrochemistry 2010, 78 (2), 122-125.

Takahashi, Y.; Shiku, H.; Murata, T.; Yasukawa, T.; Matsue, T., Transfected Single-Cell Imaging by Scanning Electrochemical Optical Microscopy with Shear Force Feedback Regulation. Anal. Chem. 2009, 81 (23), 9674-9681.

Takahashi, Y.; Miyamoto, T.; Shiku, H.; Asano, R.; Yasukawa, T.; Kumagai, I.; Matsue, T., Electrochemical Detection of Epidermal Growth Factor Receptors on a Single Living Cell Surface by Scanning Electrochemical Microscopy. Anal. Chem. 2009, 81 (7), 2785-2790.

Shiku, H.; Yamakawa, T.; Nashimoto, Y.; Takahashi, Y.; Torisawa, Y.; Yasukawa, T.; Ito-Sasaki, T.; Yokoo, M.; Abe, H.; Kambara, H.; Matsue, T., A microfluidic dual capillary probe to collect messenger RNA from adherent cells and spheroids. Anal. Biochem. 2009, 385 (1), 138-142.

Lin, Z. Y.; Takahashi, Y.; Murata, T.; Takeda, M.; Ino, K.; Shiku, H.; Matsue, T., Electrochemical Gene-Function Analysis for Single Cells with Addressable Microelectrode/Microwell Arrays. Angew. Chem. Int. Ed. 2009, 48 (11), 2044-2046.
Kunikata, R.; Takahashi, Y.; Koide, M.; Itayama, T.; Yasukawa, T.; Shiku, H.; Matsue, T., Three dimensional microelectrode array device integrating multi-channel microfluidics to realize manipulation and characterization of enzyme-immobilized polystyrene beads. Sensor Actuat B-Chem 2009, 141 (1), 256-262.

Chang, C. Y.; Takahashi, Y.; Murata, T.; Shiku, H.; Chang, H. C.; Matsue, T., Entrapment and measurement of a biologically functionalized microbead with a microwell electrode. Lab Chip 2009, 9 (9), 1185-1192.

Lin, Z.; Takahashi, Y.; Kitagawa, Y.; Umemura, T.; Shiku, H.; Matsue, T., An addressable microelectrode array for electrochemical detection. Anal. Chem. 2008, 80 (17), 6830-6833.

Nashimoto, Y.; Takahashi, Y.; Yamakawa, T.; Torisawa, Y. S.; Yasukawa, T.; Ito-Sasaki, T.; Yokoo, M.; Abe, H.; Shiku, H.; Kambara, H.; Matsue, T., Measurement of gene expression from single adherent cells and spheroids collected using fast electrical lysis. Anal. Chem. 2007, 79 (17), 6823-6830.

Luo, H. Q.; Shiku, H.; Kumagai, A.; Takahashi, Y.; Yasukawa, T.; Matsue, T., Microcontact printed diaphorase monolayer on glass characterized by atomic force microscopy and scanning electrochemical microscopy. Electrochem. Commun. 2007, 9 (11), 2703-2708.

Takahashi, Y.; Hirano, Y.; Yasukawa, T.; Shiku, H.; Yamada, H.; Matsue, T., Topographic, electrochemical, and optical images captured using standing approach mode scanning electrochemical/optical microscopy. Langmuir 2006, 22 (25), 10299-10306.

Rajendran, A.; Takahashi, Y.; Koyama, M.; Kubo, M.; Miyamoto, A., Tight-binding quantum chemical molecular dynamics simulation of mechano-chemical reactions during chemical–mechanical polishing process of SiO2 surface by CeO2 particle, Appl. Surf. Sci. 2004, 244, 34-38.

Hirata, K.; Honda, K.; Takahashi, Y., "Electrochemical imaging of hydrogen evolution reaction active sites on transition metal dichalcogenide nanosheets", Vacuum and Surface Science, 2026, 69 (8), 416-421.

Hirata, K.; Takahashi, Y., "Electrochemical imaging of catalytic active sites using scanning electrochemical cell microscopy", Vacuum and Surface Science, 2024, 67 (5), 206-211.

Honda, K.; Ida, H.; Takahashi, Y., "Development of high-speed scanning ion conductance microscopy for super-resolution live-cell imaging", Kenbikyo, 2023, 58 (2), 71-75.

Takahashi, Y., "Bioimaging by scanning probe microscopy using microelectrodes and nanopipettes", Bunseki Kagaku, 2019, 68 (1), 33-41.

Takahashi, Y., "Scanning probe microscopy 45. Atomic force microscopy ii. Scanning ion conductance microscopy: nanoscale visualization of the shape and function of living cells", Experimental Medicine, 2018, 36 (20), 3470-3471.

Takahashi, Y., "Development of electrochemical microscopes realizing super-resolution chemical imaging", Bioscience & Industry, 2018, 76 (4), 332-333.

Takahashi, Y., "Creation of nano-electrochemical microscopy and its application to single-cell evaluation", Annual Report of the Nakatani Foundation, 2018, (31), 109-114.

Takahashi, Y., "Super-resolution imaging of living cells by scanning probe microscopy", Seitai no Kagaku, 2017, 68 (5), 382-383.

Kumatani, A.; Takahashi, Y.; Miura, C.; Watanabe, T.; Inomata, H.; Munakata, H.; Shiku, H.; Kanamura, K.; Matsue, T., "Local electrochemical measurement of electrode surfaces using nano-electrochemical cell microscopy", Hyomen Kagaku, 2016, 37, 494.

Takahashi, Y., "Development of high-resolution scanning electrochemical microscopy", Chemistry & Chemical Industry, 2016, 69, 777-779.

Takahashi, Y., "Creation of nano-electrochemical microscopy visualizing nanoscale topography and chemical concentration profiles", Seibutsu Butsuri (Biophysics), 2016, 56 (3), 179-180.

Ida, H.; Takahashi, Y.; Shiku, H.; Matsue, T., "Development of scanning ion conductance microscopy for nanoscale topographic observation of living cell surfaces", Hyomen Kagaku, 2015, 36 (6), 313-318.

Takahashi, Y.; Kumatani, A.; Inomata, H.; Shiku, H.; Matsue, T., "Nanoscale imaging of charge/discharge characteristics on battery material surfaces using electrochemical cell microscopy", Energy Device, 2015, 2, 52-55.

Takahashi, Y.; Shiku, H.; Matsue, T., "Biosensing and bioimaging using micro/nanoelectrode systems", Hyomen Kagaku, 2013, 34 (9), 488-493.

Takahashi, Y.; Shiku, H.; Matsue, T., "Useful analytical techniques series, Microelectrodes (3) Application examples: Development of a combined scanning electrochemical microscopy (SECM) - scanning ion conductance microscopy (SICM) system", Electrochemistry, 2012, 80, 271-275.

Takahashi, Y., "Evaluation of living cell surfaces using scanning ion conductance microscopy", Chemical Sensors, 2011, 27 (4), 98-103.

Matsue, T.; Takahashi, Y.; Ino, K.; Shiku, H., "Enzyme imaging by scanning electrochemical microscopy", NTS Inc., 2010, pp. 112-116.

Takahashi, Y.; Shiku, H.; Yasukawa, T.; Matsue, T., "Protein patterning and analysis of interfacial phenomena", Hyomen Kagaku, 2006, 27 (10), 613-616.

Japanese Patent Application Publication No. 2024-121700, "Scanning ion conductance microscope", filed February 27, 2023 (Application No. 2023-028942). Inventor: Yasufumi Takahashi.

Japanese Patent Application Publication No. 2024-106166, "Probe for scanning probe microscope and method for fabricating the same", filed January 26, 2023 (Application No. 2023-010322). Inventors: Yasuyuki Yokota, Yuzu Kobayashi, Yasufumi Takahashi.

Japanese Patent Application Publication No. 2021-178311, "Reactor", filed January 20, 2021 (Application No. 2021-007115). Inventors: Kenji Hirai, Yasufumi Takahashi.

Japanese Patent No. 7492252, "Scanning ion conductance microscope", filed August 17, 2020 (registered May 21, 2024; Application No. 2020-137427; Publication No. 2022-033497). Inventor: Yasufumi Takahashi.

Japanese Patent Application Publication No. 2022-033486, "Scanning ion conductance microscope", filed August 17, 2020 (Application No. 2020-137405). Inventor: Yasufumi Takahashi.

Japanese Patent No. 7474428, "Microscope integrated with a film deposition apparatus", filed May 28, 2020 (registered April 17, 2024; Application No. 2020-093058; Publication No. 2021-188987). Inventors: Yasufumi Takahashi, Hideomi Koinuma, Toshihiro Sato, Nobuyuki Matsuki.

Japanese Patent No. 7304623, "Scanning ion conductance microscope enabling operando measurement", filed July 19, 2019 (registered June 29, 2023; Application No. 2019-134048; Publication No. 2021-018147). Inventor: Yasufumi Takahashi.

Japanese Patent Application Publication No. 2018-054385, "Scanning probe microscope and control method thereof", filed September 27, 2016 (Application No. 2016-188803). Inventor: Yasufumi Takahashi.

Japanese Patent No. 5467473, "Scanning electrochemical ion conductance microscope, probe thereof and method for manufacturing the probe", filed June 11, 2009 (registered February 7, 2014; Application No. 2009-140602; Publication No. 2010-261923). Inventors: Yasufumi Takahashi, Tomokazu Matsue, Hitoshi Shiku, Yumi Murakami, Kuniaki Nagamine, Andrew Shevchuk, Yuri Evgenievich Korchev.

Japanese Patent No. 5176235, "Electrochemical measurement device", filed July 3, 2008 (registered January 18, 2013; Application No. 2008-175120; Publication No. 2010-014558). Inventors: Tomokazu Matsue, Zhenyu Lin, Yasufumi Takahashi, Taizo Umemura, Yusuke Kitagawa, Tomoyuki Yasukawa, Ryota Kunikata, Hitoshi Shiku.